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-synuclein, that's a principal component of Lewy bodies, in PARK one in 1997 and parkin in PARK 2 in 1998, which is an E3 ubiquitin ligase and will cause endoplasmic reticulum (ER) pressure, recommend that dysfunction of your intracellular proteinase methods, for instance ubiquitin-proteasome program or lysosomal method, which gets rid of unneeded

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